CLB101™ Targeted-Action Probiotic
CLB101™ is a next-generation probiotic that restores a depleted keystone strain, Anaerostipes caccae, to deliver a continuous and natural source of butyrate directly to the lower gut.*
Free shipping included on all orders.
Exclusion: a shipping surcharge is required for customers in Arizona, Nebraska and Nevada only.
Please note that shipments take place Monday through Wednesday to ensure product does not get stuck in transit over a weekend. Therefore, orders received late in the week will ship the following week.
Adults take one capsule daily. Consistency is key; we recommend taking it in the morning on an empty stomach.
Store in the refrigerator.
| Week 1-3 Getting Started |
Mild changes in digestion can occur as your gut welcomes the new probiotic strain. This is a normal adjustment phase. |
|
Month 1 - 2 |
Small improvements may start to appear as your system’s balance shifts. Every gut is unique, and timing varies. |
|
Month 3+ Lasting Change |
Routine use helps stabilize your microbiome, supporting consistent digestive health. Stay on track for lasting impact. |

CLB101™ Targeted-Action Probiotic
Built on Science, Designed for Your Gut
Butyrate is a short chain fatty acid that plays a key role in gut health
How We Compare
Frequently Asked Questions
We recommend taking one CLB101™ capsule once daily on an empty stomach.
CLB101™ is intended to be a daily supplement. It can be taken indefinitely, and there are no specific recommendations on duration of usage.
We recommend you consult with your healthcare provider.
We recommend you consult with your child’s healthcare provider.
We have no specific recommendations on microbiome or other tests. You may wish to consult your healthcare practitioner for advice.
CLB101™ is temperature sensitive and for optimal potency should be stored in the refrigerator. Storage outside of the refrigerator is okay for short periods of time. However, storage for longer than a month outside of the refrigerator will impact potency.
CLB101™ is temperature sensitive and for optimal potency should be stored in the refrigerator. Traveling with CLB101™ is okay but we recommend keeping the product at room temperature or cooler.
Due to the sensitive nature of the product we are not accepting returns or exchanges once the product has been shipped. This policy ensures product integrity, safety, and quality for all customers. We stand behind the quality of our product and take great care in our manufacturing, testing, and cold-chain shipping processes. If you receive a damaged shipment or believe there was an error with your order, please contact us within 7 days of delivery at customerservice@clostrabio.com so we can address the issue promptly.
CLB101™ is currently available directly on our website as part of a limited launch.
Anaerostipes Probiotic which contains the active ingredient Anaerostipes caccae CLB101™, is also available through our commercial partner, Designs For Health.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.