Preclinical Studies
A comprehensive toxicological evaluation of Anaerostipes caccae
Peer-Reviewed Original Research Article in International Journal of Toxicology Published Aug. 29, 2025
Detailed analysis of metabolism reveals growth-rate-promoting interactions between Anaerostipes caccae and Bacteroides spp.
Peer-Reviewed Original Research in Anaerobe Published Dec. 8, 2022
Abnormal absorptive colonic motor activity in germ-free mice is rectified by butyrate, an effect possibly mediated by mucosal serotonin
Peer-Reviewed Original Research in American Journal of Physiology-Gastrointestinal and Liver Physiology Published Nov. 8, 2018
Commensal bacteria protect against food allergen sensitization
Peer-Reviewed Original Research Article in PNAS Published Sept. 9, 2014
Substrate-induced regulation of the human colonic monocarboxylate transporter, MCT1
Peer-Reviewed Research in the Journal of Physics Published Mar. 1, 2002
Colonic absorption: the importance of short chain fatty acids in man
Peer-Reviewed Research in the Scandinavian Journal of Gastroenterology Published 1984

Built on Science, Designed for Your Gut
Clinical Studies
Butyrate’s role in human health and the current progress towards its clinical application to treat gastrointestinal disease
Narrative Review in Clinical Nutrition Published Oct. 29, 2022
Integrated gut microbiome and metabolome analyses identified fecal biomarkers for bowel movement regulation by Bifidobacterium longum BB536 supplementation: A RCT
Peer-Reviewed Original Research in Computational and Structural Biotechnology Journal Published Oct. 19, 2022
Fecal microbiome and metabolome differ in healthy and food-allergic twins
Peer-Reviewed Literature Review in The Journal of Clinical Investigation Published Jan. 19, 2021
The Microbiome and Food Allergy
Literature Review in Annual Review of Immunology Published Apr. 2019
Healthy infants harbor intestinal bacteria that protect against food allergy
Peer-Reviewed Original Research Article in Nature Medicine Published Jan. 14, 2019
Temporal development of the gut microbiome in early childhood from the TEDDY study
Peer-Reviewed Original Research in Nature Published Oct. 24, 2018
The Microbiome, Timing, and Barrier Function in the Context of Allergic Disease
Peer-Reviewed Literature Review in Immunity Published Apr. 19, 2016
Lactobacillus rhamnosus GG-supplemented Formula Expands Butyrate-producing Bacterial Strains in Food Allergic Infants
Peer-Reviewed Original Research Article in The ISME Journal Published Sept. 22, 2015
The effects of butyrate enemas on visceral perception in healthy volunteers
Peer-Reviewed Original Research Article in Neurogastroenterology & Motility Published Aug. 05, 2009
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